I've had two pairs with the pads like gunchie posted, longest rides were 12 hours in each pair- back to back for 24 hours straight.

I had a little rash on the upper back of one leg- but no problems with the "normal" problem areas. It REALLY helps to get a pair of good shorts, and then ride long rides in them before your main event to get your body acclimated to the contact points etc.